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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBL2 All Species: 12.42
Human Site: T694 Identified Species: 22.78
UniProt: Q08999 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08999 NP_005602.3 1139 128367 T694 D S P S D G G T P G R M P P Q
Chimpanzee Pan troglodytes XP_523371 1139 128318 T694 D S P S D G G T P G R M P P Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535303 1139 128252 T693 D S P S D G G T P G R I P P Q
Cat Felis silvestris
Mouse Mus musculus Q64700 1135 127455 S691 S P S E G S T S G R I P P Q P
Rat Rattus norvegicus O55081 1135 127799 A691 S P S E G S T A G R I P P Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520195 1071 120785 Q638 P P S R A P S Q T L V G P A A
Chicken Gallus gallus Q90600 921 104417 T491 V M A T Y G R T A S Q S D G T
Frog Xenopus laevis NP_001084880 998 113114 P568 L P M I P A S P I V H P R V K
Zebra Danio Brachydanio rerio XP_002667000 970 107485 P540 D G D T T P E P A P P V K V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24472 845 96808 I415 V I A K L L S I I E E I E Q K
Honey Bee Apis mellifera XP_395096 1006 113492 T576 L W N A I Q S T P E G V P S C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa B9GLX8 1035 114624 L605 E E S L P R E L R R H L N S L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKZ3 1013 112157 H583 L P R E L R R H L N S L E E R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 97.1 N.A. 90.9 90 N.A. 79.8 21.8 43.2 53 N.A. 23.5 40.2 N.A. N.A.
Protein Similarity: 100 99.9 N.A. 98.7 N.A. 94.9 94.8 N.A. 87.1 38.3 61.2 65.5 N.A. 40.6 57.5 N.A. N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 6.6 6.6 N.A. 6.6 13.3 0 6.6 N.A. 0 20 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 13.3 6.6 N.A. 6.6 26.6 6.6 20 N.A. 13.3 33.3 N.A. N.A.
Percent
Protein Identity: 20.3 N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: 39.6 N.A. N.A. 39.3 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 8 8 8 0 8 16 0 0 0 0 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 31 0 8 0 24 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 8 8 0 24 0 0 16 0 0 16 8 0 16 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 16 31 24 0 16 24 8 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 16 0 0 0 0 % H
% Ile: 0 8 0 8 8 0 0 8 16 0 16 16 0 0 0 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 16 % K
% Leu: 24 0 0 8 16 8 0 8 8 8 0 16 0 0 8 % L
% Met: 0 8 8 0 0 0 0 0 0 0 0 16 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 8 39 24 0 16 16 0 16 31 8 8 24 54 24 16 % P
% Gln: 0 0 0 0 0 8 0 8 0 0 8 0 0 24 24 % Q
% Arg: 0 0 8 8 0 16 16 0 8 24 24 0 8 0 8 % R
% Ser: 16 24 31 24 0 16 31 8 0 8 8 8 0 16 0 % S
% Thr: 0 0 0 16 8 0 16 39 8 0 0 0 0 0 8 % T
% Val: 16 0 0 0 0 0 0 0 0 8 8 16 0 16 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _